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Lifitegrast (Dry Eye Syndrome) - Analysis and Forecasts to 2022
Publication Date Aug 2012
Publisher GlobalData
Product Type Report
Pages 32
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Lifitegrast (Dry Eye Syndrome) - Analysis and Forecasts to 2022

Summary

GlobalData’s pharmaceuticals report, “Lifitegrast (Dry Eye Syndrome) - Analysis and Forecasts to 2022” provides Lifitegrast sales forecasts for US and EU5. In addition, it covers detailed clinical assessment of the drug, factors impacting drug sales, competitive landscape, and analysis of sales performance during the forecast period (2016-2022). The report also includes information on Dry Eye Syndrome. This report is built using data and information sourced from GlobalData’s proprietary databases, primary and secondary research using Company’s corporate website, SEC filings, investor presentations and featured press releases, both from company and industry-specific third party sources, put together with in-house analysis, by GlobalData's team of industry experts.

Scope

- Therapy area profile including patient population for the US and EU5.
- Analysis and review of Lifitegrast including sales data
- Qualitative and quantitative assessment of market space
- Analysis of the trends, drivers and restraints shaping and defining the markets
- In-depth analysis of Lifitegrast Liquid including efficacy, safety, pricing, competition and other details which influence its sales potential
- Detailed sales forecast for 2016-2022 for Lifitegrast in the US and EU5

Reasons to buy

- Understand and capitalize by identifying products that are most likely to ensure a robust return
- Stay ahead of competition by understanding the changing competitive landscape
- Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
- Make more informed business decisions from insightful and in-depth analysis of the drug’s performance
- Examine the historical sales performance of a drug in six major markets
- Obtain sales forecast for currently marketed/pipeline drug for 2016-2022 for all six major markets

Keywords

Lifitegrast,SAR1118,SARcode Corporation,first in class,small molecule ,ophthalmic solution,Phase III,antigen-1 antagonist ,LFA-1,ocular surface inflammation,dry eye syndrome

1 Table of Contents
1 Table of Contents 2
1.1 List of Tables 3
1.2 List of Figures 3
2 Introduction 4
2.1 Dry Eye Syndrome Disease 4
2.1.1 Symptoms 4
2.2 Dry Eye Syndrome Market 5
2.3 Epidemiology 5
2.4 The Main Recognized Risk Factors 6
2.4.1 Patient Related Factors 6
2.4.2 Environmental Factors 7
2.4.3 Occupational Factors 7
2.4.4 Nutritional Factors 7
2.4.5 Systemic Medications 7
2.4.6 Topical Ophthalmic Medications 7
2.4.7 Other Factors 7
2.5 GlobalData Report Guidance 8
3 Dry Eye Syndrome: Market Characterization 9
3.1 Dry Eye Syndrome Market 9
3.2 Dry Eye Syndrome Market Forecasts and CAGR 10
3.3 Drivers and Barriers of Dry Eye Syndrome Therapeutics Market 10
3.3.1 Ageing Population 10
3.3.2 Changing lifestyle 10
3.3.3 High Unmet Need 11
3.3.4 New Product Launches 11
4 Classification of Dry Eye Syndrome 12
4.1 Classification based on Severity Grading Scheme 12
4.2 Classification based on Signs and Symptoms 12
4.2.1 Mild Dry Eye 12
4.2.2 Moderate Dry Eye 12
4.2.3 Severe Dry Eye 12
5 Treatment for Dry Eye Syndrome 13
5.1 Pharmacological Treatment 13
5.1.1 Tear Supplements 13
5.1.2 Anti-inflammatory Agents 14
5.1.3 Mucolytics 14
5.1.4 Autologous Serum 14
5.1.5 Secretagogues and Mucin Enhancing Agents 15
5.1.6 Fatty Acid Supplements 15
5.1.7 Antibiotics 15
5.1.8 Hormonal Therapy 15
5.2 Surgical Interventions 15
5.2.1 Punctal Occlusion Surgery 15
5.2.2 Salivary Gland Autotransplantation 15
5.3 Non Surgical Interventions 15
6 Lifitegrast 16
6.1 Introduction 16
6.2 Mechanism of Action 16
6.3 Clinical Studies 16
6.4 Factors Affecting Sales of Lifitegrast 17
6.4.1 High Unmet need for Dry Eye Syndrome 17
6.4.2 Approval in Europe 17
6.4.3 Superior Efficacy 17
6.4.4 Superior Safety Profile 17
6.5 Drug Evaluation 18
6.5.1 Drug Risk Benefit Score 18
6.5.2 Intensity of Competition 19
6.6 Sales Forecasts 19
6.6.1 Target Patient Pool for Lifitegrast 19
6.6.2 Dosing 19
6.6.3 Market Penetration 19
6.6.4 Annual Cost of Therapy 20
6.6.5 Global Sales Projections of Lifitegrast 21
7 Dry Eye Syndrome Market: Appendix 29
7.1 Market Definitions 29
7.2 List of Abberiviations 29
7.3 Research Methodology 29
7.3.1 Coverage 29
7.3.2 Secondary Research 30
7.3.3 Forecasting 30
7.3.4 Number of Patients Approved to Take the Drug 30
7.3.5 Net Penetration of Drug 30
7.3.6 Net Annual Dosing 31
7.3.7 Annual Cost of Therapy 31
7.4 Drug Sales Estimates Model 31
7.5 Contact Us 31
7.6 Disclaimer 31
7.7 Sources 32

List of Tables
1.1 List of Tables
Table 1: Dry Eye Syndrome, Global, Major Marketed Products 9
Table 2: Dry Eye Syndrome, Global, Major Pipeline Products in Phase III 9
Table 3: Dry Eye Syndrome - Severity Grading Scheme 12
Table 4: Lifitegrast, Dry Eye Syndrome, Phase II, Clinical Trial Results 17
Table 5: Drug Risk Benefit Score of Lifitegrast 18
Table 6: Annual Cost of Therapy of Lifitegrast 20
Table 7: Lifitegrast, Dry Eye Syndrome, Global, Sales Estimates ($m) , 2014-2022 21
Table 8: Lifitegrast, Dry Eye Syndrome, The US, Sales Estimates ($m) , 2014-2022 22
Table 9: Lifitegrast, Dry Eye Syndrome, The UK, Sales Estimates ($m) , 2016-2022 23
Table 10: Lifitegrast, Dry Eye Syndrome, France, Sales Estimates ($m), 2016-2022 24
Table 11: Lifitegrast, Dry Eye Syndrome, Germany, Sales Estimates ($m) , 2016-2022 25
Table 12: Lifitegrast, Dry Eye Syndrome, Italy, Sales Estimates ($m) , 2016-2022 26
Table 13: Lifitegrast, Dry Eye Syndrome, Spain, Sales Estimates ($m) , 2016-2022 27

List of Figures
1.2 List of Figures
Figure 1: Normal Eye and Dry Eye 4
Figure 2: Cascade of Events Leading to Dry Eye 5
Figure 3: Age -standardized prevalence ratio in the US men and women 6
Figure 4: Dry Eye Syndrome, Global, Market Size Forecasts ($bn), 2011-2022 10
Figure 5: Therapeutic Choice for Dry Eye Syndrome 13
Figure 6: Drug Model Diagram of Lifitegrast 19
Figure 7: Lifitegrast, Dry Eye Syndrome, Global, Sales Estimates ($m), 2014-2022 21
Figure 8: Lifitegrast, Dry Eye Syndrome, The US, Sales Estimates ($m), 2014-2022 22
Figure 9: Lifitegrast, Dry Eye Syndrome, The UK, Sales Estimates ($m), 2016-2022 23
Figure 10: Lifitegrast, Dry Eye Syndrome, France, Sales Estimates ($m), 2016-2022 24
Figure 11: Lifitegrast, Dry Eye Syndrome, Germany, Sales Estimates ($m), 2016-2022 25
Figure 12: Lifitegrast, Dry Eye Syndrome, Italy, Sales Estimates ($m), 2016-2022 26
Figure 13: Lifitegrast, Dry Eye Syndrome, Spain, Sales Estimates ($m), 2016-2022 27
Figure 14: Lifitegrast, Global, Sales Distribution by Country (%), 2022 28
Figure 15: Patients Approved for the Drug 30

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